An anti-tuberculosis compound screen using a zebrafish infection model identifies an aspartyl-tRNA synthetase inhibitor

Finding new anti-tuberculosis compounds with convincing in vivo activity is an ongoing global challenge to fight the emergence of multidrug-resistant Mycobacterium tuberculosis isolates. In this study, we exploited the medium-throughput capabilities of the zebrafish embryo infection model with Mycob...

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Detalles Bibliográficos
Autores principales: Habjan, Eva, Ho, Vien Q. T., Gallant, James, van Stempvoort, Gunny, Jim, Kin Ki, Kuijl, Coen, Geerke, Daan P., Bitter, Wilbert, Speer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713996/
https://www.ncbi.nlm.nih.gov/pubmed/34643222
http://dx.doi.org/10.1242/dmm.049145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713996/
https://www.ncbi.nlm.nih.gov/pubmed/34643222
http://dx.doi.org/10.1242/dmm.049145

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