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Isotretinoin Induced Hyperlipidemia and Impact of Leptin Gene rs 7799039 Polymorphism in Safety of Acne Patients

BACKGROUND: Acne vulgaris (AV) is a chronic inflammatory disease that affects the pilosebaceous unit. Leptin (LEP) gene polymorphisms is associated with higher risk of multiple disorders. Insulin-like growth factor-1 (IGF-1) exerts comedogenic effect by stimulating the sebaceous glands. Isotretinoin...

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Detalles Bibliográficos
Autores principales: Mohamed, Amal A, Hassnine, Alshymaa, Elsayed, Amr, Montaser, Mahmoud, Ismail, Yasmeen, El-Demery, Ahmed, Sultan, Eman, Abdel Aziz, Rania S, Eldemiry, Eman, Hagag, Radwa, El-Kholy, Amal A, Salah, Eman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714009/
https://www.ncbi.nlm.nih.gov/pubmed/34992430
http://dx.doi.org/10.2147/PGPM.S341723