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14-3-3 proteins promote synaptic localization of N-methyl d-aspartate receptors (NMDARs) in mouse hippocampal and cortical neurons

One of the core pathogenic mechanisms for schizophrenia is believed to be dysfunction in glutamatergic synaptic transmissions, particularly hypofunction of N-methyl d-aspartate receptors (NMDARs). Previously we showed that 14-3-3 functional knockout mice exhibit schizophrenia-associated behaviors ac...

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Detalles Bibliográficos
Autores principales: Lee, Gloria S., Zhang, Jiajing, Wu, Yuying, Zhou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714094/
https://www.ncbi.nlm.nih.gov/pubmed/34962957
http://dx.doi.org/10.1371/journal.pone.0261791