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Endothelial cell–derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway

The abnormal proliferation of vascular smooth muscle cells (VSMCs) plays an important role in the development and progression of diabetic vascular complications. In high-glucose (HG) conditions, endothelial cells (ECs) act as the first barrier to damaging stimuli and trigger a multi-response, includ...

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Detalles Bibliográficos
Autores principales: Wang, Shaohua, Shi, Min, Li, Jiao, Zhang, Yuanyuan, Wang, Wenjing, Xu, Peixin, Li, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714133/
https://www.ncbi.nlm.nih.gov/pubmed/34887361
http://dx.doi.org/10.18632/aging.203742