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Metabolomic profiling of plasma from middle-aged and advanced-age male mice reveals the metabolic abnormalities of carnitine biosynthesis in metallothionein gene knockout mice

Metallothionein (MT) is a family of low molecular weight, cysteine-rich proteins that regulate zinc homeostasis and have potential protective effects against oxidative stress and toxic metals. MT1 and MT2 gene knockout (MTKO) mice show shorter lifespans than wild-type (WT) mice. In this study, we ai...

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Detalles Bibliográficos
Autores principales: Kadota, Yoshito, Yano, Asuka, Kawakami, Takashige, Sato, Masao, Suzuki, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714139/
https://www.ncbi.nlm.nih.gov/pubmed/34851303
http://dx.doi.org/10.18632/aging.203731