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The Neoepitopes on Methylglyoxal- (MG-) Glycated Fibrinogen Generate Autoimmune Response: Its Role in Diabetes, Atherosclerosis, and Diabetic Atherosclerosis Subjects

OBJECTIVES: In diabetes mellitus, hyperglycemia-mediated nonenzymatic glycosylation of fibrinogen protein plays a crucial role in the pathogenesis of micro- and macrovascular complications especially atherosclerosis via the generation of advanced glycation end products (AGEs). Methylglyoxal (MG) ind...

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Detalles Bibliográficos
Autores principales: Rehman, Shahnawaz, Song, Jiantao, Faisal, Mohammad, Alatar, Abdulrahman A., Akhter, Firoz, Ahmad, Saheem, Hu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714332/
https://www.ncbi.nlm.nih.gov/pubmed/34970417
http://dx.doi.org/10.1155/2021/6621568