Cargando…
MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease
Oxidative stress is a major risk factor for Alzheimer's disease (AD), which is characterized by brain atrophy, amyloid plaques, neurofibrillary tangles, and loss of neurons. 8-Oxoguanine, a major oxidatively generated nucleobase highly accumulated in the AD brain, is known to cause neurodegener...
Autores principales: | Mizuno, Yuri, Abolhassani, Nona, Mazzei, Guianfranco, Sakumi, Kunihiko, Saito, Takashi, Saido, Takaomi C., Ninomiya, Toshiharu, Iwaki, Toru, Yamasaki, Ryo, Kira, Jun-ichi, Nakabeppu, Yusaku |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714343/ https://www.ncbi.nlm.nih.gov/pubmed/34970419 http://dx.doi.org/10.1155/2021/8635088 |
Ejemplares similares
-
Corrigendum to “MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease”
por: Mizuno, Yuri, et al.
Publicado: (2023) -
A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App
(NL−F/NL−F) knock‐in mouse model
por: Mazzei, Guianfranco, et al.
Publicado: (2021) -
Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
por: Castillo, Erika, et al.
Publicado: (2017) -
Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
por: Castillo, Erika, et al.
Publicado: (2021) -
A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA
por: Ushijima, Yasuhiro, et al.
Publicado: (2005)