Blood Neurofilament Light Chain as a Potential Biomarker for Central and Peripheral Nervous Toxicity in Rats

Neurotoxicity is a principal concern in nonclinical drug development. However, standardized and universally accepted fluid biomarkers for evaluating neurotoxicity are lacking. Increasing clinical evidence supports the potential use of neurofilament light (NfL) chain as a biomarker of several neurode...

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Detalles Bibliográficos
Autores principales: Sano, Tomoya, Masuda, Yasushi, Yasuno, Hironobu, Shinozawa, Tadahiro, Watanabe, Takeshi, Kakehi, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714368/
https://www.ncbi.nlm.nih.gov/pubmed/34677616
http://dx.doi.org/10.1093/toxsci/kfab122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714368/
https://www.ncbi.nlm.nih.gov/pubmed/34677616
http://dx.doi.org/10.1093/toxsci/kfab122

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