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Sphingosine Kinase 1 Plays an Important Role in Atorvastatin-Mediated Anti-Inflammatory Effect against Acute Lung Injury

Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) inhibitor and inhibits cholesterol synthesis. Recently, atorvastatin also showed anti-inflammatory effect in acute lung injury, ameliorating pulmonary gas-blood exchanging function. Sphingosine kinase 1 plays a cen...

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Detalles Bibliográficos
Autores principales: Wu, Lan, Cheng, Yan, Peng, Shunxiang, Zhang, Wensheng, Zhang, Chaoxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714370/
https://www.ncbi.nlm.nih.gov/pubmed/34970075
http://dx.doi.org/10.1155/2021/9247285