Cargando…
Sphingosine Kinase 1 Plays an Important Role in Atorvastatin-Mediated Anti-Inflammatory Effect against Acute Lung Injury
Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) inhibitor and inhibits cholesterol synthesis. Recently, atorvastatin also showed anti-inflammatory effect in acute lung injury, ameliorating pulmonary gas-blood exchanging function. Sphingosine kinase 1 plays a cen...
Autores principales: | Wu, Lan, Cheng, Yan, Peng, Shunxiang, Zhang, Wensheng, Zhang, Chaoxiong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714370/ https://www.ncbi.nlm.nih.gov/pubmed/34970075 http://dx.doi.org/10.1155/2021/9247285 |
Ejemplares similares
-
Atorvastatin Improves the Propionic Acid-Induced Autism in Rats: The Roles of Sphingosine-1-Phosphate and Anti-inflammatory Action
por: Durankuş, Ferit, et al.
Publicado: (2023) -
The role of the sphingosine axis in immune regulation: A dichotomy in the
anti-inflammatory effects between sphingosine kinase 1 and sphingosine kinase 2-dependent
pathways
por: Ishay, Yuval, et al.
Publicado: (2021) -
Atorvastatin protects against cerebral ischemia/reperfusion injury through anti-inflammatory and antioxidant effects
por: Tu, Qiuyun, et al.
Publicado: (2014) -
Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury
por: Xu, Xin, et al.
Publicado: (2017) -
UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1
por: Epshtein, Yulia, et al.
Publicado: (2023)