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Extracellular HMGB1 Induced Glomerular Endothelial Cell Injury via TLR4/MyD88 Signaling Pathway in Lupus Nephritis

Previously, our study showed that HMGB1 was significantly elevated in the blood and located in the glomerular endothelium in LN patients. But whether extracellular HMGB1 is involved in the injury of glomerular endothelial cells (GECs) in LN still needs further investigation. Firstly, we detected the...

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Detalles Bibliográficos
Autores principales: Yu, Tian, Xiaojuan, Feng, Jinxi, Liu, Xinyan, Miao, Jie, Xu, Yuexin, Tian, Qingjuan, Liu, Wei, Zhang, Cunyang, Gu, Jie, Huang, Lunbi, Wu, Hang, Zhao, Shuxia, Liu, Huifang, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714399/
https://www.ncbi.nlm.nih.gov/pubmed/34970076
http://dx.doi.org/10.1155/2021/9993971