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Bilineal evolution of a U2AF1-mutated clone associated with acquisition of distinct secondary mutations

Rare hematologic malignancies display evidence of both myeloid and lymphoid differentiation. Here, we describe such a novel bilineal event discovered in an adult woman with B-lymphoblastic leukemia (BLL). At the time of BLL diagnosis, the patient had a normal karyotype and a bulk sequencing panel id...

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Detalles Bibliográficos
Autores principales: Montgomery, Nathan D., Galeotti, Jonathan, Johnson, Steven M., Commander, Leah, Weimer, Eric T., Chandra, Pranil K., Nazir, Tariq, Alexander, Thomas B., Zeidner, Joshua F., Foster, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714722/
https://www.ncbi.nlm.nih.gov/pubmed/34581783
http://dx.doi.org/10.1182/bloodadvances.2021005308