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Bilineal evolution of a U2AF1-mutated clone associated with acquisition of distinct secondary mutations
Rare hematologic malignancies display evidence of both myeloid and lymphoid differentiation. Here, we describe such a novel bilineal event discovered in an adult woman with B-lymphoblastic leukemia (BLL). At the time of BLL diagnosis, the patient had a normal karyotype and a bulk sequencing panel id...
Autores principales: | Montgomery, Nathan D., Galeotti, Jonathan, Johnson, Steven M., Commander, Leah, Weimer, Eric T., Chandra, Pranil K., Nazir, Tariq, Alexander, Thomas B., Zeidner, Joshua F., Foster, Matthew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714722/ https://www.ncbi.nlm.nih.gov/pubmed/34581783 http://dx.doi.org/10.1182/bloodadvances.2021005308 |
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