Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl ester as ATP-competitive inhibitors of BRAF: A bioinformatics study

Serine/threonine-protein kinase B-raf (BRAF) plays a significant role in regulating cell division and proliferation through MAPK/ERK pathway. The constitutive expression of wild-type BRAF (BRAF(WT)) and its mutant forms, especially V600E (BRAF(V600E)), has been linked to multiple cancers. Various sy...

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Detalles Bibliográficos
Autores principales: Malik, Vidhi, Kumar, Vipul, Kaul, Sunil C., Wadhwa, Renu, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714769/
https://www.ncbi.nlm.nih.gov/pubmed/35028596
http://dx.doi.org/10.1016/j.crstbi.2021.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714769/
https://www.ncbi.nlm.nih.gov/pubmed/35028596
http://dx.doi.org/10.1016/j.crstbi.2021.11.004

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