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Integrative Transcriptomics Reveals Activation of Innate Immune Responses and Inhibition of Inflammation During Oral Immunotherapy for Egg Allergy in Children

We previously reported the results of a randomized, open-label trial of egg oral immunotherapy (OIT) in 50 children where 44% were desensitized and 46% were partially desensitized after 8 months of treatment. Here we focus on cell-mediated molecular mechanisms driving desensitization during egg OIT....

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Detalles Bibliográficos
Autores principales: Karisola, Piia, Palosuo, Kati, Hinkkanen, Victoria, Wisgrill, Lukas, Savinko, Terhi, Fyhrquist, Nanna, Alenius, Harri, Mäkelä, Mika J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714802/
https://www.ncbi.nlm.nih.gov/pubmed/34975829
http://dx.doi.org/10.3389/fimmu.2021.704633