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Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway

Our previous study manifested that lanthanum chloride (LaCl(3)) can enhance the anticancer ability of cisplatin (DDP) in ovarian cancer cells. Here, ovarian cancer cells SKOV3 and SKOV3/DDP were subjected to DDP and LaCl(3). Cell viability, apoptosis, DNA repair, and PI3K/Akt pathway were detected....

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Detalles Bibliográficos
Autores principales: Fang, Shanyu, Zhang, Ping, Chen, Xinping, Liu, Fujun, Wang, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714849/
https://www.ncbi.nlm.nih.gov/pubmed/34977076
http://dx.doi.org/10.3389/fmed.2021.776876