Metabolic adaptations in cancers expressing isocitrate dehydrogenase mutations

The most frequently mutated metabolic genes in human cancer are those encoding the enzymes isocitrate dehydrogenase 1 (IDH1) and IDH2; these mutations have so far been identified in more than 20 tumor types. Since IDH mutations were first reported in glioma over a decade ago, extensive research has...

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Detalles Bibliográficos
Autores principales: Hvinden, Ingvild Comfort, Cadoux-Hudson, Tom, Schofield, Christopher J., McCullagh, James S.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714851/
https://www.ncbi.nlm.nih.gov/pubmed/35028610
http://dx.doi.org/10.1016/j.xcrm.2021.100469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714851/
https://www.ncbi.nlm.nih.gov/pubmed/35028610
http://dx.doi.org/10.1016/j.xcrm.2021.100469

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