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Soluble antigens derived from Coxiella burnetii elicit protective immunity in three animal models without inducing hypersensitivity
Q fever is caused by the intracellular bacterium Coxiella burnetii, for which there is no approved vaccine in the United States. A formalin-inactivated whole-cell vaccine (WCV) from virulent C. burnetii NMI provides single-dose long-lived protection, but concerns remain over vaccine reactogenicity....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714860/ https://www.ncbi.nlm.nih.gov/pubmed/35028605 http://dx.doi.org/10.1016/j.xcrm.2021.100461 |