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Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147

BACKGROUND: Angiogenesis is a major contributor to the development of inflammation during Rheumatoid arthritis (RA), as the vascularization of the pannus provides nutrients and oxygen for the infiltrating immune cells and proliferating synoviocytes. Tocilizumab (TCZ) is an anti-IL-6 receptor antibod...

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Detalles Bibliográficos
Autores principales: Zisman, Devy, Safieh, Mirna, Simanovich, Elina, Feld, Joy, Kinarty, Amalia, Zisman, Liron, Gazitt, Tal, Haddad, Amir, Elias, Muna, Rosner, Itzhak, Kaly, Lisa, Rahat, Michal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714881/
https://www.ncbi.nlm.nih.gov/pubmed/34975837
http://dx.doi.org/10.3389/fimmu.2021.739592