Yi-Zhi-Fang-Dai Formula Exerts Neuroprotective Effects Against Pyroptosis and Blood–Brain Barrier–Glymphatic Dysfunctions to Prevent Amyloid-Beta Acute Accumulation After Cerebral Ischemia and Reperfusion in Rats

Background: The dysfunctional blood–brain barrier (BBB)–glymphatic system is responsible for triggering intracerebral amyloid-beta peptide (Aβ) accumulation and acts as the key link between ischemic stroke and dementia dominated by Alzheimer’s disease (AD). Recently, pyroptosis in cerebral ischemia...

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Detalles Bibliográficos
Autores principales: Lyu, Zhongkuan, Li, Qiyue, Yu, Zhonghai, Chan, Yuanjin, Fu, Lei, Li, Yaming, Zhang, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714930/
https://www.ncbi.nlm.nih.gov/pubmed/34975487
http://dx.doi.org/10.3389/fphar.2021.791059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714930/
https://www.ncbi.nlm.nih.gov/pubmed/34975487
http://dx.doi.org/10.3389/fphar.2021.791059

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