UDCA Inhibits Hypoxic Hepatocellular Carcinoma Cell–Induced Angiogenesis Through Suppressing HIF-1α/VEGF/IL-8 Intercellular Signaling

Background: A hypoxic microenvironment may induce angiogenesis and promote the development of hepatocellular carcinoma (HCC). The aim of this study was to evaluate whether ursodeoxycholic acid (UDCA) may inhibit hypoxic HCC cell–induced angiogenesis and the possible mechanisms. Methods: Tube formati...

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Detalles Bibliográficos
Autores principales: Lin, Wanfu, Li, Shu, Meng, Yongbin, Huang, Guokai, Liang, Shufang, Du, Juan, Liu, Qun, Cheng, Binbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714963/
https://www.ncbi.nlm.nih.gov/pubmed/34975472
http://dx.doi.org/10.3389/fphar.2021.755394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714963/
https://www.ncbi.nlm.nih.gov/pubmed/34975472
http://dx.doi.org/10.3389/fphar.2021.755394

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