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Human lung cDC1 drive increased perforin-mediated NK cytotoxicity in chronic obstructive pulmonary disease
In chronic obstructive pulmonary disease (COPD), lung natural killer cells (NKs) lyse autologous lung epithelial cells in vitro, but underlying mechanisms and their relationship to epithelial cell apoptosis in vivo are undefined. Although this cytolytic capacity of lung NKs depends on priming by den...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715029/ https://www.ncbi.nlm.nih.gov/pubmed/34704847 http://dx.doi.org/10.1152/ajplung.00322.2020 |