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High fat stems tumor immune surveillance

In a recent issue of Cell Stem Cell, Beyaz et al. show that high-fat diets promote tumorigenesis by reducing major histocompatibility complex (MHC) class II expression in intestinal stem cells. Dietary modulation of epithelial MHC II expression is regulated by the gut microbiota.

Detalles Bibliográficos
Autores principales: Caruso, Roberta, Chen, Grace Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715059/
https://www.ncbi.nlm.nih.gov/pubmed/35028622
http://dx.doi.org/10.1016/j.xcrm.2021.100483