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Improved l-phenylglycine synthesis by introducing an engineered cofactor self-sufficient system

l-phenylglycine (L-phg) is a valuable non-proteinogenic amino acid used as a precursor to β-lactam antibiotics, antitumor agent taxol and many other pharmaceuticals. L-phg synthesis through microbial bioconversion allows for high enantioselectivity and sustainable production, which will be of great...

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Detalles Bibliográficos
Autores principales: Wang, Pengchao, Zhang, Xiwen, Tao, Yucheng, Lv, Xubing, Cheng, Shengjie, Liu, Chengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715069/
https://www.ncbi.nlm.nih.gov/pubmed/35024478
http://dx.doi.org/10.1016/j.synbio.2021.12.008