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Improved l-phenylglycine synthesis by introducing an engineered cofactor self-sufficient system
l-phenylglycine (L-phg) is a valuable non-proteinogenic amino acid used as a precursor to β-lactam antibiotics, antitumor agent taxol and many other pharmaceuticals. L-phg synthesis through microbial bioconversion allows for high enantioselectivity and sustainable production, which will be of great...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715069/ https://www.ncbi.nlm.nih.gov/pubmed/35024478 http://dx.doi.org/10.1016/j.synbio.2021.12.008 |