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The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136

OBJECTIVE: Methylglyoxal (MG) is a highly reactive α-oxoaldehyde that glycates proteins. MG has been linked to the development of diabetic complications: MG is the major precursor of advanced glycation end products (AGEs), a risk marker for diabetic complications in humans. Furthermore, flies and fi...

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Detalles Bibliográficos
Autores principales: Cortizo, Fabiola Garcia, Pfaff, Daniel, Wirth, Angela, Schlotterer, Andrea, Medert, Rebekka, Morgenstern, Jakob, Weber, Tobias, Hammes, Hans-Peter, Fleming, Thomas, Nawroth, Peter Paul, Freichel, Marc, Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715127/
https://www.ncbi.nlm.nih.gov/pubmed/34838714
http://dx.doi.org/10.1016/j.molmet.2021.101406