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The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136
OBJECTIVE: Methylglyoxal (MG) is a highly reactive α-oxoaldehyde that glycates proteins. MG has been linked to the development of diabetic complications: MG is the major precursor of advanced glycation end products (AGEs), a risk marker for diabetic complications in humans. Furthermore, flies and fi...
Autores principales: | Cortizo, Fabiola Garcia, Pfaff, Daniel, Wirth, Angela, Schlotterer, Andrea, Medert, Rebekka, Morgenstern, Jakob, Weber, Tobias, Hammes, Hans-Peter, Fleming, Thomas, Nawroth, Peter Paul, Freichel, Marc, Teleman, Aurelio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715127/ https://www.ncbi.nlm.nih.gov/pubmed/34838714 http://dx.doi.org/10.1016/j.molmet.2021.101406 |
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