Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis

BACKGROUND: Autophagosome, the central organelle in autophagy process, can assemble via canonical pathway mediated by LC3-II, the lipidated form of autophagy-related protein LC3/ATG8, or noncanonical pathway mediated by the small GTPase Rab9. Canonical autophagy is essential for exocrine pancreas ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Mareninova, Olga A., Dillon, Dustin L., Wightman, Carli J.M., Yakubov, Iskandar, Takahashi, Toshimasa, Gaisano, Herbert Y., Munson, Keith, Ohmuraya, Masaki, Dawson, David, Gukovsky, Ilya, Gukovskaya, Anna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715155/
https://www.ncbi.nlm.nih.gov/pubmed/34610499
http://dx.doi.org/10.1016/j.jcmgh.2021.09.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715155/
https://www.ncbi.nlm.nih.gov/pubmed/34610499
http://dx.doi.org/10.1016/j.jcmgh.2021.09.017

Ejemplares similares