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Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis
BACKGROUND: Autophagosome, the central organelle in autophagy process, can assemble via canonical pathway mediated by LC3-II, the lipidated form of autophagy-related protein LC3/ATG8, or noncanonical pathway mediated by the small GTPase Rab9. Canonical autophagy is essential for exocrine pancreas ho...
Autores principales: | Mareninova, Olga A., Dillon, Dustin L., Wightman, Carli J.M., Yakubov, Iskandar, Takahashi, Toshimasa, Gaisano, Herbert Y., Munson, Keith, Ohmuraya, Masaki, Dawson, David, Gukovsky, Ilya, Gukovskaya, Anna S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715155/ https://www.ncbi.nlm.nih.gov/pubmed/34610499 http://dx.doi.org/10.1016/j.jcmgh.2021.09.017 |
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