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Left-handed cardiac looping by cell chirality is mediated by position-specific convergent extensions

In the embryonic heart development of mammals and birds, a straight initial heart tube undergoes left-handed helical looping, which is a remarkable and puzzling event. We are interested in the mechanism of this chiral helical looping. Recently, observations were reported that myocardial cells in the...

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Detalles Bibliográficos
Autor principal: Honda, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715179/
https://www.ncbi.nlm.nih.gov/pubmed/34695385
http://dx.doi.org/10.1016/j.bpj.2021.10.025