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Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology

Frontotemporal lobar degeneration (FTLD) is a heterogeneous spectrum of age-associated neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) and TDP-43 (FTLD-TDP) proteinopathies. These distinct proteinopathies are often clinically indistinguishable during life, po...

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Detalles Bibliográficos
Autores principales: Tisdall, M. Dylan, Ohm, Daniel T., Lobrovich, Rebecca, Das, Sandhitsu R., Mizsei, Gabor, Prabhakaran, Karthik, Ittyerah, Ranjit, Lim, Sydney, McMillan, Corey T., Wolk, David A., Gee, James, Trojanowski, John Q., Lee, Edward B., Detre, John A., Yushkevich, Paul, Grossman, Murray, Irwin, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715243/
https://www.ncbi.nlm.nih.gov/pubmed/34952351
http://dx.doi.org/10.1016/j.nicl.2021.102913