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Native extracellular matrix orientation determines multipotent vascular stem cell proliferation in response to cyclic uniaxial tensile strain and simulated stent indentation

Cardiovascular disease is the leading cause of death worldwide, with multipotent vascular stem cells (MVSC) implicated in contributing to diseased vessels. MVSC are mechanosensitive cells which align perpendicular to cyclic uniaxial tensile strain. Within the blood vessel wall, collagen fibers const...

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Detalles Bibliográficos
Autores principales: Mathieu, P.S., Fitzpatrick, E., Di Luca, M., Cahill, P.A., Lally, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715293/
https://www.ncbi.nlm.nih.gov/pubmed/35005255
http://dx.doi.org/10.1016/j.bbrep.2021.101183