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Structure-function relationship between soluble epoxide hydrolases structure and their tunnel network

Enzymes with buried active sites maintain their catalytic function via a single tunnel or tunnel network. In this study we analyzed the functionality of soluble epoxide hydrolases (sEHs) tunnel network, by comparing the overall enzyme structure with the tunnel’s shape and size. sEHs were divided int...

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Detalles Bibliográficos
Autores principales: Mitusińska, Karolina, Wojsa, Piotr, Bzówka, Maria, Raczyńska, Agata, Bagrowska, Weronika, Samol, Aleksandra, Kapica, Patryk, Góra, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715294/
https://www.ncbi.nlm.nih.gov/pubmed/35024092
http://dx.doi.org/10.1016/j.csbj.2021.10.042