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Cannabinoid control of gingival immune activation in chronically SIV-infected rhesus macaques involves modulation of the indoleamine-2,3-dioxygenase-1 pathway and salivary microbiome
BACKGROUND: HIV/SIV-associated periodontal disease (gingivitis/periodontitis) (PD) represents a major comorbidity affecting people living with HIV (PLWH) on combination anti-retroviral therapy (cART). PD is characterized by chronic inflammation and dysbiosis. Nevertheless, the molecular mechanisms a...
Autores principales: | McDew-White, Marina, Lee, Eunhee, Alvarez, Xavier, Sestak, Karol, Ling, Binhua J, Byrareddy, Siddappa N, Okeoma, Chioma M, Mohan, Mahesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715300/ https://www.ncbi.nlm.nih.gov/pubmed/34954656 http://dx.doi.org/10.1016/j.ebiom.2021.103769 |
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