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Studying macrophage activation in immune-privileged lens through CSF-1 protein intravitreal injection in mouse model

Macrophage (MΦ) activation and promotion of fibrosis are critical processes in lens capsule healing after injury. Here, we detail a protocol that induces MΦ2 formation within the vitreous body of the eye. Our procedure combines the use of an intravitreal injection of a growth factor (CSF-1) and immu...

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Detalles Bibliográficos
Autores principales: Li, Yuting, Acosta, Francisca M., Quan, Yumeng, Li, Zhen, Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715327/
https://www.ncbi.nlm.nih.gov/pubmed/35005642
http://dx.doi.org/10.1016/j.xpro.2021.101060