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Mapping atypical UV photoproducts in vitro and across the S. cerevisiae genome

Exposure to ultraviolet (UV) light induces DNA damage, predominantly cyclobutane pyrimidine dimers (CPD) and 6,4-photoproducts (6,4-PP), as well as rare, atypical photoproducts at thymidine-adenine (TA) sequences. We have recently shown ‘TA’ photoproducts are induced in UV-irradiated oligonucleotide...

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Detalles Bibliográficos
Autores principales: Bohm, Kaitlynne A., Sivapragasam, Smitha, Wyrick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715331/
https://www.ncbi.nlm.nih.gov/pubmed/35005641
http://dx.doi.org/10.1016/j.xpro.2021.101059