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Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis in vitro

Previous reports highlighted the neurotoxic effects caused by some motif-specific anti-PrP(C) antibodies in vivo and in vitro. In the current study, we investigated the detailed alterations of the proteome with liquid chromatography–mass spectrometry following direct application of anti-PrP(C) antib...

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Detalles Bibliográficos
Autores principales: Adhikari, Utpal Kumar, Sakiz, Elif, Habiba, Umma, Mikhael, Meena, Senesi, Matteo, David, Monique Antoinette, Guillemin, Gilles J., Ooi, Lezanne, Karl, Tim, Collins, Steven, Tayebi, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715334/
https://www.ncbi.nlm.nih.gov/pubmed/35005289
http://dx.doi.org/10.1016/j.heliyon.2021.e08644