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The Histone H3 K4me3, K27me3, and K27ac Genome-Wide Distributions Are Differently Influenced by Sex in Brain Cortexes and Gastrocnemius of the Alzheimer’s Disease PSAPP Mouse Model

Background: Women represent the majority of Alzheimer’s disease patients and show typical symptoms. Genetic, hormonal, and behavioral mechanisms have been proposed to explain sex differences in dementia prevalence. However, whether sex differences exist in the epigenetic landscape of neuronal tissue...

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Detalles Bibliográficos
Autores principales: Casciaro, Francesca, Persico, Giuseppe, Rusin, Martina, Amatori, Stefano, Montgomery, Claire, Rutkowsky, Jennifer R., Ramsey, Jon J., Cortopassi, Gino, Fanelli, Mirco, Giorgio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715457/
https://www.ncbi.nlm.nih.gov/pubmed/34968250
http://dx.doi.org/10.3390/epigenomes5040026