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Kinetics and Mechanism of Fentanyl Dissociation from the μ-Opioid Receptor
[Image: see text] Driven by illicit fentanyl, opioid related deaths have reached the highest level in 2020. Currently, an opioid overdose is resuscitated by the use of naloxone, which competitively binds and antagonizes the μ-opioid receptor (mOR). Thus, knowledge of the residence times of opioids a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715493/ https://www.ncbi.nlm.nih.gov/pubmed/34977892 http://dx.doi.org/10.1021/jacsau.1c00341 |