Cargando…

Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides

[Image: see text] Here, we report the electrochemical detection of single-point mutations using solid-phase isothermal primer elongation with redox-labeled oligonucleotides. A single-base mutation associated with resistance to rifampicin, an antibiotic commonly used for the treatment of Mycobacteriu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz, Mayreli, Jauset-Rubio, Miriam, Skouridou, Vasso, Machado, Diana, Viveiros, Miguel, Clark, Taane G., Simonova, Anna, Kodr, David, Hocek, Michal, O’Sullivan, Ciara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715531/
https://www.ncbi.nlm.nih.gov/pubmed/34797987
http://dx.doi.org/10.1021/acssensors.1c01710