HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia

BACKGROUND: Pulmonary fibrosis is thought to be driven by recurrent alveolar epithelial injury which leads to the differentiation of fibroblasts into α-smooth muscle actin (α-SMA)-expressing myofibroblasts and subsequent deposition of extracellular matrix (ECM). Transforming growth factor beta-1 (TG...

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Detalles Bibliográficos
Autores principales: Trivlidis, Joshua, Aloufi, Noof, Al-Habeeb, Fatmah, Nair, Parameswaran, Azuelos, Ilan, Eidelman, David H., Baglole, Carolyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715577/
https://www.ncbi.nlm.nih.gov/pubmed/34963461
http://dx.doi.org/10.1186/s12931-021-01916-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715577/
https://www.ncbi.nlm.nih.gov/pubmed/34963461
http://dx.doi.org/10.1186/s12931-021-01916-4

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