MiR-423-5p activated by E2F1 promotes neovascularization in diabetic retinopathy by targeting HIPK2

BACKGROUND: Diabetic retinopathy (DR) is a diabetic complication and the primary cause of blindness in the world. However, the treatments of DR are challenging given its complicated pathogenesis. Here, we investigated the molecular mechanisms of DR by focusing on the function of E2F1/miR-423-5p/HIPK...

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Detalles Bibliográficos
Autores principales: Xiao, Qing, Zhao, Yinu, Sun, Hongjing, Xu, Jia, Li, Wenjie, Gao, Limo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715594/
https://www.ncbi.nlm.nih.gov/pubmed/34963484
http://dx.doi.org/10.1186/s13098-021-00769-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715594/
https://www.ncbi.nlm.nih.gov/pubmed/34963484
http://dx.doi.org/10.1186/s13098-021-00769-7

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