Astrocytic C–X–C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

BACKGROUND: Pathological interactions between β-amyloid (Aβ) and tau drive synapse loss and cognitive decline in Alzheimer’s disease (AD). Reactive astrocytes, displaying altered functions, are also a prominent feature of AD brain. This large and heterogeneous population of cells are increasingly re...

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Detalles Bibliográficos
Autores principales: Perez-Nievas, Beatriz G., Johnson, Louisa, Beltran-Lobo, Paula, Hughes, Martina M., Gammallieri, Luciana, Tarsitano, Francesca, Myszczynska, Monika A., Vazquez-Villasenor, Irina, Jimenez-Sanchez, Maria, Troakes, Claire, Wharton, Stephen B., Ferraiuolo, Laura, Noble, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715604/
https://www.ncbi.nlm.nih.gov/pubmed/34963475
http://dx.doi.org/10.1186/s12974-021-02371-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715604/
https://www.ncbi.nlm.nih.gov/pubmed/34963475
http://dx.doi.org/10.1186/s12974-021-02371-0

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