A deletion in the N gene of SARS-CoV-2 may reduce test sensitivity for detection of SARS-CoV-2

One SARS-CoV-2-positive sample demonstrated impaired detection of the N1 target by RT-PCR using US CDC primer/probe sets. A 3 nucleotide deletion was discovered that overlaps the forward primer binding site. This finding underscores the importance of continued SARS-CoV-2 mutation surveillance and as...

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Detalles Bibliográficos
Autores principales: Wang, Huanyu, Jean, Sophonie, Wilson, Sarah A., Lucyshyn, Jocelyn M., McGrath, Sean, Wilson, Richard K., Magrini, Vincent, Leber, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715644/
https://www.ncbi.nlm.nih.gov/pubmed/35045382
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715644/
https://www.ncbi.nlm.nih.gov/pubmed/35045382
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115631

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