Liraglutide Inhibits Osteoclastogenesis and Improves Bone Loss by Downregulating Trem2 in Female Type 1 Diabetic Mice: Findings From Transcriptomics

BACKGROUND: The mechanisms of bone fragility in type 1 diabetes (T1D) are not fully understood. Whether glucagon-like peptide-1 receptor (GLP-1R) agonists could improve bone quality in T1D context also remains elusive. AIMS: We aimed to explore the possible mechanisms of bone loss in T1D and clarify...

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Detalles Bibliográficos
Autores principales: Yu, Jie, Shi, Yan-Chuan, Ping, Fan, Li, Wei, Zhang, Hua-Bing, He, Shu-Li, Zhao, Yuan, Xu, Ling-Ling, Li, Yu-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715718/
https://www.ncbi.nlm.nih.gov/pubmed/34975749
http://dx.doi.org/10.3389/fendo.2021.763646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715718/
https://www.ncbi.nlm.nih.gov/pubmed/34975749
http://dx.doi.org/10.3389/fendo.2021.763646

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