1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications

Autologous, antigen-specific, tolerogenic dendritic cells (tolDCs) are presently assessed to reverse and possibly cure autoimmune diseases such as type 1 diabetes (T1D). Good Manufacturing Practice production and clinical implementation of such cell therapies critically depend on their stability and...

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Detalles Bibliográficos
Autores principales: van Megen, Kayleigh M., Chen, Zhuo, Joosten, Antoinette M., Laban, Sandra, Zwaginga, Jaap-Jan, Natarajan, Rama, Nikolic, Tatjana, Roep, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715888/
https://www.ncbi.nlm.nih.gov/pubmed/33461863
http://dx.doi.org/10.1016/j.jcyt.2020.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715888/
https://www.ncbi.nlm.nih.gov/pubmed/33461863
http://dx.doi.org/10.1016/j.jcyt.2020.12.003

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