Disruption of Hars2 in Cochlear Hair Cells Causes Progressive Mitochondrial Dysfunction and Hearing Loss in Mice

Mutations in a number of genes encoding mitochondrial aminoacyl-tRNA synthetases lead to non-syndromic and/or syndromic sensorineural hearing loss in humans, while their cellular and physiological pathology in cochlea has rarely been investigated in vivo. In this study, we showed that histidyl-tRNA...

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Detalles Bibliográficos
Autores principales: Xu, Pengcheng, Wang, Longhao, Peng, Hu, Liu, Huihui, Liu, Hongchao, Yuan, Qingyue, Lin, Yun, Xu, Jun, Pang, Xiuhong, Wu, Hao, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715924/
https://www.ncbi.nlm.nih.gov/pubmed/34975414
http://dx.doi.org/10.3389/fncel.2021.804345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715924/
https://www.ncbi.nlm.nih.gov/pubmed/34975414
http://dx.doi.org/10.3389/fncel.2021.804345

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