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Upregulation of acid sensing ion channels is associated with esophageal hypersensitivity in GERD

Proton pump inhibitors (PPIs) are the mainstay of therapy for gastroesophageal reflux disease (GERD) but up to 60% of patients have inadequate response to therapy. Acid sensing ion channels (ASICs) play important roles in nociception. This study aimed to investigate whether the increased expression...

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Detalles Bibliográficos
Autores principales: Han, Xu, Zhang, Yawen, Lee, Allen, Li, Zhaoshen, Gao, Jun, Wu, Xiaoyin, Zhao, Jiulong, Wang, Hui, Chen, Di, Zou, Duowu, Owyang, Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715981/
https://www.ncbi.nlm.nih.gov/pubmed/34918385
http://dx.doi.org/10.1096/fj.202100606R