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Blastocyst development after fertilization with in vitro spermatids derived from nonhuman primate embryonic stem cells

OBJECTIVE: To demonstrate that functional spermatids can be derived in vitro from nonhuman primate pluripotent stem cells. DESIGN: Green fluorescent protein-labeled, rhesus macaque nonhuman primate embryonic stem cells (nhpESCs) were differentiated into advanced male germ cell lineages using a modif...

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Detalles Bibliográficos
Autores principales: Khampang, Sujittra, Cho, In Ki, Punyawai, Kanchana, Gill, Brittany, Langmo, Jacqueline N., Nath, Shivangi, Greeson, Katherine W., Symosko, Krista M., Fowler, Kristen L., Tian, Siran, Statz, John P., Steves, Alyse N., Parnpai, Rangsun, White, Michael A., Hennebold, Jon D., Orwig, Kyle E., Simerly, Calvin R., Schatten, Gerald, Easley, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716017/
https://www.ncbi.nlm.nih.gov/pubmed/34970648
http://dx.doi.org/10.1016/j.xfss.2021.09.001