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Establishment of quantitative RNAi-based forward genetics in Entamoeba histolytica and identification of genes required for growth

While Entamoeba histolytica remains a globally important pathogen, it is dramatically understudied. The tractability of E. histolytica has historically been limited, which is largely due to challenging features of its genome. To enable forward genetics, we constructed and validated the first genome-...

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Detalles Bibliográficos
Autores principales: Bettadapur, Akhila, Hunter, Samuel S., Suleiman, Rene L., Ruyechan, Maura C., Huang, Wesley, Barbieri, Charles G., Miller, Hannah W., Tam, Tammie S. Y., Settles, Matthew L., Ralston, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716031/
https://www.ncbi.nlm.nih.gov/pubmed/34843592
http://dx.doi.org/10.1371/journal.ppat.1010088